Overview

• High-resolution genomic tools map genes involved in malaria parasite's sexual differentiation.
• Study reveals ApiAP2 transcription factors as crucial regulators of gametocyte development.
• Research identifies novel 'driver' genes for male and female cell fates in Plasmodium falciparum.
• Findings pave the way for innovative transmission-blocking malaria therapies.
• Data offers evolutionary insights into sex determination in ancient eukaryotic microbes.