New Fluorescent Sensors Cross Blood-Brain Barrier, Enhancing Alzheimer's Detection

Researchers develop exosome-based delivery system for ATP sensors, improving brain imaging in mouse models of Alzheimer's disease.

Fluorescent sensors encapsulated in exosomes successfully cross the blood-brain barrier in mice.
The sensors detect low ATP levels in brain regions affected by Alzheimer's, aiding diagnosis.
Exosome delivery is nearly four times more efficient than conventional methods.
The new technique shows promise for non-invasive live brain imaging.
Researchers aim to adapt the method for other clinically relevant neurotransmitters.