New FLiRT COVID Variants Dominate Globally

FLiRT variants, including KP.2 and JN.1, show mutations that may enhance transmissibility but are not linked to increased severity.

FLiRT variants are named for specific spike protein mutations: F456L, V1104L, and R346T.
KP.2 is now the most common variant in the U.S., with JN.1 leading globally.
Current vaccines are expected to offer some protection against these variants.
COVID-related hospitalizations and emergency visits have not increased significantly.
Experts will meet on June 5 to discuss new vaccine designs targeting these variants.