Overview

• OLAH enzyme linked to severe outcomes in multiple respiratory infections, including influenza and COVID-19.
• High OLAH expression correlates with fatal disease progression, while low levels are found in mild cases.
• Mouse models show reduced severity of viral infections when OLAH is absent.
• Potential for OLAH to serve as a biomarker for early risk assessment and personalized treatment strategies.
• Ongoing research aims to develop OLAH-based diagnostic methods to improve patient prognosis.