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New Compound Boosts Naloxone's Effectiveness Against Opioid Overdoses

Researchers discover a molecule that enhances naloxone's potency and duration, offering hope for better overdose treatments.

  • The compound, named 368, makes naloxone 7.6 times more effective at blocking opioid receptors.
  • Naloxone combined with 368 can last ten times longer in the body than naloxone alone.
  • The combination treatment reduces withdrawal symptoms in mice.
  • Researchers screened 4.5 billion molecules to identify the promising compound.
  • It may take 10-15 years for the naloxone-enhancing drug to reach the market.
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