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New Brazilian Bat Coronavirus With SARS‑CoV‑2‑Like Furin Site Reported in Preprint

Researchers urge expanded wildlife surveillance in the under-sampled Americas pending peer review.

Overview

  • Scientists sequenced a previously unknown betacoronavirus, dubbed BRZ batCoV, from a Parnell’s mustached bat collected in Brazil in 2019.
  • The virus’s spike protein contains a functional furin cleavage site differing by one amino acid from the site in SARS‑CoV‑2.
  • Based on genetic analysis, the authors propose BRZ batCoV represents a new subgenus within the betacoronavirus genus.
  • The study, released on bioRxiv, is based on genomic data from gut tissue and the virus has not been isolated or tested for infectivity.
  • Researchers and outside virologists highlight major surveillance gaps in Latin America and caution that human risk cannot be inferred without further lab studies.