Overview

• The principle of 'selectively advantageous instability' (SAI) posits that cellular volatility provides evolutionary benefits.
• Instability in biological components allows for genetic diversity and adaptability.
• SAI may contribute to aging by enabling the coexistence of normal and mutated genes, some of which may be harmful.
• The concept challenges traditional views that stability is energetically preferable for living organisms.
• SAI's implications extend to fields like chaos theory and synthetic cell design.