New analysis finds limited benefit and higher risks of daily aspirin for primary prevention of heart attack and stroke

Multiple studies find limited protective effect of daily low-dose aspirin for preventing first heart attack or stroke in healthy older adults without prior cardiovascular events.
Higher rates of bleeding, especially brain bleeding, found with daily aspirin use, outweighing the potential benefits.
US Preventive Services Task Force now recommends against starting daily aspirin for primary prevention in adults 60 and older.
For adults with multiple cardiovascular risk factors, the decision on aspirin use is less clear and should involve considering both risks and benefits.
For most people with a prior heart attack or stroke, experts agree daily aspirin should remain part of standard care.