New Algorithm Revolutionizes Enzyme Engineering
Researchers develop a method that uses evolutionary history to enhance enzyme performance, with broad industrial applications.
- Scientists created an algorithm to introduce targeted mutations in enzymes, improving their activity and stability.
- The method focuses on beta-lactamase, an enzyme crucial for antibiotic resistance.
- Up to 84 mutations were successfully introduced, significantly enhancing enzyme functionality.
- The engineered enzymes retained their 3D structure despite extensive sequence changes.
- Potential applications include food production, plastic degradation, and healthcare.