Overview
- Memphis Depay, now playing for Corinthians, will earn his 99th cap for the Netherlands and is five goals away from becoming the nation's all-time leading scorer.
- Frenkie de Jong has been declared fully fit to play after overcoming an ankle injury and a recent illness, marking his return to the national team after missing Euro 2024.
- Ryan Gravenberch has withdrawn from the squad following an injury sustained during Liverpool's Carabao Cup final loss, as confirmed by the Royal Dutch Football Association.
- Justin Kluivert is set to continue his national team comeback after a six-year absence, with Ronald Koeman praising his development in the Premier League.
- The Netherlands will host Spain in Rotterdam for the first leg on March 20, 2025, before traveling to Valencia for the second leg on March 23, 2025.