Nagaland University Identifies Plant Antioxidant That Speeds Diabetic Wound Healing in Preclinical Study

Overview

• Researchers report that oral sinapic acid accelerated wound closure in diabetic animal models and improved metabolic measures.
• The study, published in Nature Scientific Reports, links the compound’s effects to activation of the SIRT1 pathway tied to tissue repair, angiogenesis and inflammation control.
• An inverted dose-response was observed, with 20 mg/kg outperforming 40 mg/kg, underscoring the need for careful dosing studies.
• Sinapic acid is a naturally occurring antioxidant found in edible plants, which the team says could support an affordable oral approach if validated in humans.
• The investigators plan pilot clinical trials, while noting that no human safety or efficacy data have been reported yet.