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Mutated Drug-Resistant Bacteria Proliferate on International Space Station

New research reveals that strains of Enterobacter bugandensis on the ISS have become genetically distinct from their Earth counterparts, raising concerns about astronaut health.

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NASA has confirmed the International Space Station is home to drug-resistant bacteria that has mutated and separated itself from its Earth counterparts.
Illustrative workflow showcasing the process of comparative genomics analysis of Enterobacter bugandensis, evaluating its prevalence and metabolic interactions within the microbial community, and its successful adaptation within the ISS habitat. Image credit: Sengupta et al., doi: 10.1186/s40168-024-01777-1.

Overview

  • Studies show Enterobacter bugandensis, a multi-drug resistant bacterium, has mutated under ISS conditions, becoming functionally distinct.
  • The bacteria's adaptation includes increased antibiotic resistance and potential virulence, posing a risk to astronauts' immune systems.
  • Genomic analysis of 13 ISS strains reveals significant differences from Earth strains, suggesting unique evolutionary paths.
  • The unique ISS environment, including microgravity and elevated radiation, facilitates rapid microbial mutations.
  • Researchers emphasize the need for robust preventive measures to protect astronaut health from these pathogens.