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12m ago

MRI Confirms Nick Bosa Tore Right ACL; 49ers Star Out for 2025 Season

An MRI showed a clean tear in his right knee, forcing San Francisco to lean on Bryce Huff plus other edge depth.

Sep 21, 2025; Santa Clara, California, USA; San Francisco 49ers defensive end Nick Bosa (97) on the field during warm ups prior to a game against the Arizona Cardinals during the first half at Levi's Stadium. Mandatory Credit: Cary Edmondson-Imagn Images
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Nathan Ray Seebeck-Imagn Images
Sam Navarro-Imagn Images

Overview

  • He suffered the injury late in the first quarter of Sunday’s 16-15 win over the Cardinals and was seen giving a thumbs-down as he headed to the locker room.
  • Initial sideline checks suggested the ACL was intact, but follow-up imaging on Monday confirmed a tear.
  • The clean ACL tear will require reconstructive surgery, ending his season.
  • Imaging indicated no additional ligament damage in the knee.
  • With Bosa out, the 49ers are expected to elevate Bryce Huff, rookie Mykel Williams, Sam Okuayinonu and Yetur Gross-Matos while assessing further roster options.