Particle.news

Download on the App Store

Mouse Study Links Daily Red Meat to Worsened Colitis via Microbiome and Immune Shifts

The short, high‑exposure mouse model offers mechanistic clues without defining human intake thresholds.

Image
Red meat diets have been found to promote colonic inflammation

Overview

  • Mice fed pork, beef or mutton daily for two weeks developed more severe DSS‑induced colitis than controls.
  • Red meat diets reduced Akkermansia, Faecalibacterium, Streptococcus and Lactococcus and increased Clostridium and Mucispirillum in the gut.
  • Colonic tissue showed greater infiltration of neutrophils and macrophages along with elevated pro‑inflammatory cytokines after red meat feeding.
  • The peer‑reviewed research from Capital Medical University was published in Molecular Nutrition & Food Research.
  • Authors caution that findings from a short, high‑exposure murine model may not translate directly to people and suggest reducing red meat intake pending human studies.