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Mother Arrested for 2020 Bronx Twin Infant Murders After Genetic Genealogy Breakthrough

Investigators used genetic genealogy to match DNA from a discarded can to crime-scene evidence, leading to charges against the twins’ mother.

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Stephanie Castillo is pictured in police custody leaving the NYPD's 44th Precinct stationhouse on Friday, June 19, 2025, in the Bronx. (Barry Williams / New York Daily News)
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Overview

  • Stephanie Castillo, 36, was arrested July 25 at a Bronx homeless shelter and charged with six counts each of murder and manslaughter in her newborn twins’ deaths.
  • The full-term twin boys were discovered on November 9, 2020, behind 1460 College Avenue in the Claremont section of the Bronx with blunt force trauma to the head and spine.
  • NYPD detectives maintained the cold case for five years through annual vigils, public appeals and escalating reward offers despite no eyewitnesses or functioning surveillance.
  • A breakthrough came when investigators used investigative genetic genealogy to link Castillo’s DNA from a discarded drink can to blood evidence at the scene.
  • Officers arranged a funeral for the infants, naming them Zeke and Zane, and Castillo’s arraignment in Bronx court is pending.