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Modest Gait Changes Slow Knee Cartilage Loss in Osteoarthritis

A simple, low-cost walking modification delivered slower cartilage loss alongside reduced pain in a 68-person trial highlighting the need for larger, longer-term validation.

Overview

  • A one-year randomized trial in The Lancet Rheumatology assigned 34 adults with mild-to-moderate knee osteoarthritis to adjust their foot angle inward or outward by 5–10° during at least 20 minutes of daily walking while 34 controls maintained their natural gait.
  • MRI assessments at trial end showed that participants who altered their foot angle experienced significantly slower loss of medial knee cartilage compared with the control group.
  • Those who modified their walking reported an average pain reduction of 2.5 points on a 10-point scale, an effect the authors equate with relief from over-the-counter pain medications.
  • Study leaders characterize the gait-adjustment approach as a simple, noninvasive, and relatively low-cost early-stage therapy with potential to delay knee replacement surgery.
  • Researchers emphasize that confirmation through larger, more diverse, and longer-duration trials along with development of AI-assisted personalization tools is required before clinical adoption.