Particle.news
Download on the App Store

Moderna, Merck Melanoma Vaccine Shows Durable Five-Year Benefit as Stock Hits 52-Week High

Investors weigh promising Phase 2b results against the need for Phase 3 confirmation and a cautious analyst outlook.

Overview

  • In a Phase 2b study with five-year follow-up, intismeran autogene plus Keytruda reduced the risk of recurrence or death by about 49% versus Keytruda alone.
  • Moderna shares jumped roughly 16% to around $50, setting a new 52-week high following the data release.
  • Moderna and Merck plan to share additional follow-up analyses of primary and secondary endpoints at an upcoming medical meeting.
  • The Phase 3 adjuvant melanoma trial (INTerpath-001) is fully enrolled, while two Phase 3 NSCLC studies and multiple Phase 2 trials in renal and bladder cancers are enrolling.
  • Analyst sentiment remains neutral despite the rally, with a consensus Hold rating and an average price target near $29.93.