MIT Study Reveals How Propofol Induces Unconsciousness

Researchers identify disruption in brain's stability-excitability balance as key mechanism behind common anesthetic's effects.

Propofol disrupts the brain's ability to balance excitability and stability, leading to unconsciousness.
Researchers used the DeLASE technique to analyze neuronal activity in non-human primates.
Findings could improve anesthesia monitoring and treatment for psychiatric disorders.
The study suggests other anesthetics might share similar mechanisms through different pathways.
Published in Neuron, the study enhances understanding of anesthesia's impact on neural dynamics.