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6mo ago

MIT Researchers Develop Nanodiscs for Non-Invasive Brain Stimulation

These tiny magnetic discs could offer a safer alternative to traditional deep brain stimulation by eliminating the need for implants.

The magnetic core of the nanodisc is magnetostrictive, which means it changes shape when magnetized. The rainbow nanodisc on the right is changing shape, allowing for the pink brain neuron to be stimulated.
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Overview

  • Tiny magnetic nanodiscs, developed by MIT scientists, offer a less invasive method for brain stimulation compared to traditional electrode implants.
  • The nanodiscs, measuring about 250 nanometers, can be injected into specific brain areas and activated externally using a magnetic field.
  • Initial tests on mice show the potential of these discs to stimulate brain regions associated with reward and motor control, similar to implanted electrodes.
  • Despite promising results, further research is needed to enhance the conversion of magnetic effects into electrical impulses for effective human use.
  • Future steps include large animal safety studies to move towards potential clinical applications in treating neurological conditions like Parkinson's disease.