MIT Researcher Runs Doom on E. coli Bacteria Display

A single playthrough would take approximately 600 years due to the slow frame rate.

MIT biotechnology PhD student researcher Lauren 'Ren' Ramlan has created a display using E. coli bacteria to run the game Doom.
The display is a 32x48 1-bit monochromatic display that uses bacteria infused with a fluorescent protein, with each one effectively acting as a single pixel.
It takes 70 minutes for the cells to illuminate an image, and then another eight hours and 20 minutes to go dark so it could be reset for the next frame.
According to Ramlan's calculations, it would take around 600 years to complete an entire playthrough of Doom on the gut bacteria cells.
Despite the lengthy time to completion, Ramlan described the project as 'enjoyable' and a proof of concept that Doom can run on anything.