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MIT Demonstrates Injectable, Self-Implanting Brain Implants That Stimulate Neurons in Mice

Cell‑fused microelectronics crossed the intact blood–brain barrier to enable micrometer‑scale, wirelessly powered neuromodulation.

Overview

  • Peer‑reviewed results published in Nature Biotechnology describe autonomous delivery and operation of the tiny devices in mouse brains.
  • Electronics were chemically fused to monocytes, allowing immune camouflage and trafficking to inflammation‑targeted regions across the intact barrier.
  • After self‑implantation, an external near‑infrared transmitter powered the chips to provide highly localized electrical stimulation.
  • Biocompatibility tests indicated the implants integrated among neurons without detectable effects on cognition or motor function.
  • The research team launched Cahira Technologies and says it aims to pursue human trials in about three years, contingent on larger‑animal studies, long‑term safety data, and regulatory review.