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Missouri Favored as Kansas–Missouri Rivalry Resumes Saturday

Oddsmakers back the Tigers by about a touchdown, reflecting model projections that tilt toward Missouri.

Aug. 29, 2025; Lawrence, Kansas; Kansas football mascot Little Jay is seen on the sideline during a game against Wagner at David Booth Kansas Memorial Stadium.
Aug. 29, 2025; Lawrence, Kansas; Kansas football offensive lineman Kael Farkes (58) gets ready for the snap during a game against Wagner at David Booth Kansas Memorial Stadium.
Can Jalon Daniels and the Kansas Jayawks beat Missouri? College football Week 2 picks, predictions and odds preview the game on Saturday, Sept. 6.

Overview

  • Kickoff is set for Sept. 6 at 2:30 p.m. CT at Memorial Stadium in Columbia on ESPN2, with Kansas 2-0 and Missouri 1-0.
  • BetMGM lists Missouri as a 6.5-point favorite with a -220 moneyline, Kansas at +180, and a total of 50.5.
  • ESPN gives Missouri a 64% win probability, while Dimers.com projects a 63% chance for the Tigers.
  • Kansas’ game-week depth chart names Jalon Daniels the starting quarterback, with Cole Ballard and Isaiah Marshall as backups.
  • StubHub resale listings for the matchup started around $209 as of the morning of Aug. 31.