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Microrobots Deliver Chemotherapy Directly to Lung Tumors in Mice

UC San Diego engineers develop algae-based microrobots that improve survival rates by targeting metastatic lung cancer.

  • Microrobots combine green algae with drug-filled nanoparticles to navigate lung tissue and deliver chemotherapy.
  • The nanoparticles are coated with red blood cell membranes to evade the immune system and prolong drug retention.
  • In treated mice, the microrobots extended median survival time from 27 to 37 days compared to control groups.
  • The technology builds on previous successes in treating pneumonia, showcasing its versatility for lung diseases.
  • Researchers aim to advance to larger animal trials and eventually human clinical trials.
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