Overview

• The MHRA has logged more than 40 pregnancy reports among women using GLP-1 receptor agonist jabs including 26 linked to Mounjaro and warned that the drugs must not be taken during pregnancy, when trying to conceive or during breastfeeding.
• Women are advised to use effective contraception such as implants, coils or condoms while on these medications and to continue contraception for up to two months after stopping before attempting to get pregnant.
• Patients starting Mounjaro should use additional barrier methods like condoms for the first four weeks and after any dose increase because the injection may reduce the absorption of oral contraceptives in overweight users.
• The MHRA reminded users that weight-loss jabs must be prescribed by healthcare professionals and cautioned against buying them from unregulated sellers such as beauty salons or social media platforms.
• The updated guidance also highlights rare but serious risks including acute pancreatitis and stresses that these drugs are approved for medical conditions, not cosmetic or unmonitored use.