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MHRA Issues Festive-Season Alert on Alcohol–Medicine Risks and Paracetamol Overdose

The notice offers precautionary guidance for the holiday period, with a call to report side effects through the Yellow Card scheme.

Overview

  • The regulator warns that combining alcohol with many prescription or over‑the‑counter medicines can increase dizziness, slow reactions and raise the risk of falls and accidents.
  • People are urged not to double up on paracetamol, as many cold and flu remedies already contain it and accidental overdose can result.
  • The guidance advises checking the Patient Information Leaflet every time because advice on interactions, including alcohol, can change.
  • Expired or leftover medicines should be cleared out and not shared, with pharmacists able to advise on safe disposal.
  • The MHRA asks the public to report suspected side effects via the Yellow Card scheme, with medical advice available through NHS 111 or emergency services if required.