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Metabolic Syndrome Linked to 24% Higher Risk of Dementia Before 65, Study Finds

New research highlights the cumulative impact of metabolic health factors on young-onset dementia risk, with women and younger adults most affected.

Blood pressure, blood sugar, and cholesterol are among the conditions that may impact young dementia risk, study suggests.
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Researchers found each component of metabolic syndrome was associated with an increased risk of dementia, which was cumulative. Credit: Neuroscience News

Overview

  • A study of nearly two million Koreans found that metabolic syndrome increases the risk of young-onset dementia by 24%, with stronger effects in women and younger participants.
  • Each component of metabolic syndrome—such as high blood pressure, high blood sugar, obesity, and abnormal cholesterol—was individually linked to higher dementia risk.
  • Participants with all five components of metabolic syndrome faced a 70% higher risk of developing dementia before age 65 compared to those without the condition.
  • The research, published in *Neurology*, was observational and cannot establish causation, but it underscores the importance of early lifestyle and medical interventions.
  • Experts recommend addressing metabolic syndrome through balanced diets, regular exercise, routine health screenings, and, when necessary, medications to reduce dementia risk.