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Mediterranean Diet Plus Calorie Cuts and Exercise Lowers Type 2 Diabetes Risk by 31% in Six-Year Trial

Randomized results from Spain show that a Mediterranean pattern with structured calorie cuts, activity guidance, plus counseling lowered diabetes incidence in high-risk older adults.

Walking for 45 minutes daily, at least six days a week was a key part of the lifestyle changes that reduced the risk of type 2 diabetes.
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The final preparation of a healthy salad and at the end the woman pours olive oil.

Overview

  • The PREDIMED-Plus randomized clinical trial followed 4,746 adults for six years and found a 31% lower incidence of type 2 diabetes in the intervention group versus a control group on a standard Mediterranean diet.
  • Participants were ages 55 to 75, overweight or obese, had metabolic syndrome, and were free of diabetes at baseline.
  • The intervention paired a Mediterranean eating pattern with about 600 fewer calories per day, moderate physical activity such as brisk walking and strength/balance work, and professional weight-loss support.
  • Researchers reported modest absolute benefits—about three fewer cases per 100 people over the study period—alongside greater average reductions in weight (3.3 kg) and waist circumference (3.6 cm) than in controls.
  • Findings, published in Annals of Internal Medicine, come from Europe’s largest nutrition and lifestyle randomized trial and involved sustained adherence supported by frequent counseling sessions.