Overview

• President Trump urged pregnant women not to take Tylenol and portrayed autism as a crisis, while also questioning routine vaccine schedules at a White House event.
• An FDA letter to clinicians said a causal relationship between acetaminophen and autism has not been established, advised weighing risks and benefits, and signaled review of labeling and communications.
• Major medical groups, including ACOG, SMFM and the AAP, reaffirmed that acetaminophen is appropriate for treating fever or significant pain in pregnancy and cautioned that untreated illness poses known risks to mother and fetus.
• Scientists whose work was cited by the administration said their findings were misinterpreted, noting that rigorous designs such as a large Swedish sibling-comparison study do not support a causal link.
• HHS signaled interest in promoting leucovorin as an autism intervention despite limited evidence, and reporting highlighted ties between RFK Jr.–aligned organizations and supplement companies selling non‑medical pain remedies, as parents and clinicians warned against mother‑blaming and misinformation.