Overview
- A study of 537 infants hospitalised with severe respiratory disease in winter 2024–25 found a 72% reduction in RSV admissions when mothers were vaccinated at least 14 days before delivery compared with 58% protection at any time in pregnancy.
- Researchers from the Universities of Edinburgh and Leicester reported their findings in The Lancet Child & Adolescent Health after analysing data from 30 hospitals across England and Scotland.
- Antibodies generated by the maternal RSV vaccine cross the placenta and provide infants with protection against severe RSV infection for up to six months after birth.
- Despite high effectiveness, only around half of eligible pregnant women are receiving the vaccine, which the NHS offers from 28 weeks of gestation.
- The NHS is expanding access to the RSV jab for pregnant women and adults aged 75–79 as part of its broader multi-modal RSV prevention strategy under the NHS 10-Year Plan.