Mast Cells' Unexpected Role in Allergic Reactions

New research reveals mast cells trap and recycle neutrophils, enhancing inflammation and immune response.

• Researchers discovered that mast cells can engulf and trap neutrophils during allergic reactions.
• This trapping process, termed 'mast cell intracellular trap' (MIT), was observed using advanced microscopy techniques.
• Trapped neutrophils eventually die, and their components are recycled by mast cells to boost their function.
• The findings could lead to new treatments for chronic allergic conditions and inflammatory diseases.
• The study highlights the complex interactions between immune cells and their roles in inflammation.

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