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Margaret Qualley Reveals Year-Long Skin Damage from 'The Substance' Prosthetics

The actress shared how prosthetics for the award-winning horror film caused severe acne and impacted her next project.

  • Margaret Qualley disclosed on the 'Happy Sad Confused' podcast that prosthetics used during the filming of 'The Substance' caused extensive skin irritation and acne that took a year to heal.
  • Due to the damage, her face was omitted from certain shots in the film, with creative framing used instead.
  • The lingering acne from the prosthetics carried over to her next project, 'Kinds of Kindness,' where it aligned with the portrayal of one of her characters.
  • 'The Substance,' a body horror film exploring themes of beauty standards, has garnered critical acclaim and earned Demi Moore a Golden Globe for her performance.
  • Both Qualley and Moore underwent grueling prosthetic transformations during the production, with Moore spending up to nine hours in the makeup chair for her role.
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