Overview

• Trimethylaminuria is caused by an FM03 gene mutation that prevents the breakdown of trimethylamine, resulting in a pungent fish-like smell from breath, sweat and urine.
• Symptoms first appeared at age 18, leading Davies to miss family events, including her cousin’s funeral, and to withdraw from employment opportunities.
• Her concerns were initially dismissed as psychological before she obtained a formal TMAU diagnosis in June 2023.
• Metabolic Support UK records only about 100 diagnosed TMAU cases in the UK, indicating the condition may often go unrecognised.
• She manages daily life by following a strict low-choline diet that excludes fish, eggs, red meat and processed foods, though strict dietary limits can be challenging.