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Low-calorie diets linked to increased depression risk in men and overweight adults

Analysis of NHANES data links severe calorie restriction to nutrient deficiencies that may worsen depressive symptoms.

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Experts recommend consulting a medical professional before attempting to lose weight.
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Overview

  • The Canadian-led study in BMJ Nutrition Prevention & Health analyzed diet and depression questionnaires from 28,525 US adults in NHANES data.
  • Participants following low-calorie diets reported higher scores for depressive symptoms, with the strongest associations in men and those classified as overweight.
  • Researchers warn that unsupervised calorie cutting can cause deficiencies in protein, vitamins and minerals that contribute to mood disturbances.
  • Diet quality influenced depression risk, as Mediterranean-style eaters had lower symptom scores and those consuming more ultra-processed foods showed higher risk.
  • Experts call for balanced, personalized dietary recommendations and further randomized trials to clarify how calorie restriction impacts mental health.