Louisville Upsets No. 11 Clemson to Secure Historic Victory

The Cardinals defeated Clemson for the first time, shaking up ACC standings and playoff hopes.

Lousiville's Isaac Brown rushed for a career-high 151 yards, including a decisive 45-yard touchdown in the fourth quarter.
Quarterback Tyler Shough contributed with a somersault touchdown and led the Cardinals to a 33-21 victory.
The win marked Louisville's first-ever victory over Clemson since joining the Atlantic Coast Conference nine years ago.
Clemson's offense struggled to capitalize on their 450 total yards, hindered by two blocked field goal attempts.
The defeat significantly impacts Clemson's chances for an ACC title and a College Football Playoff spot, requiring outside help to advance.