Overview
- The 59-point margin was the sixth-largest in program history, according to team statistician Kelly Dickey.
 - South Carolina State shot 22.8% and committed 25 turnovers, while Louisville shot 53.2% with 23 assists on 33 field goals.
 - Sophomore Khani Rooths set a career high with 20 points and matched his best with seven rebounds.
 - Five Cardinals scored in double figures, led by Isaac McKneely with 17, J’Vonne Hadley with 13, Ryan Conwell with 12, and five-star freshman Mikel Brown Jr. with 11 and six assists.
 - Preseason ranked for the first time in six years, Louisville returns Thursday to host Jackson State.