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Lori Coble, Mother Who Lost 3 Children in 2007 Crash, Dies at 48

She succumbed to stage 4 glioblastoma diagnosed in July after a rapid decline that led to hospice care by December.

Overview

  • Her husband, Chris Coble, announced on Facebook that she died Jan. 21 at 9:25 p.m.
  • Chris first noticed clumsiness and stroke-like symptoms in June 2025, leading to a July diagnosis of an aggressive glioblastoma.
  • Lori underwent two brain surgeries; the second caused loss of control on her left side followed by a stroke and about 40 days in the hospital.
  • Doctors later treated a significant brain infection and then a lung infection with pneumonia before she transitioned to home hospice.
  • The family, remembered for losing three young children in a 2007 truck crash and later welcoming triplets, has received broad community support, with fundraising totaling $323,755.