Overview

• Updated analyses emphasize 150–300 minutes of moderate aerobic activity each week plus strength training, with even brisk walking offering measurable benefits.
• Whole‑foods eating patterns such as Mediterranean or DASH are linked to fewer premature deaths than processed, sugar‑heavy diets, according to Global Burden of Disease findings.
• High‑quality relationships, purpose and an optimistic outlook strongly predict better health in late life, while loneliness is associated with higher mortality risk.
• Biological‑age tests remain imprecise, and many clinic‑marketed therapies—from cryotherapy to young‑plasma and stem‑cell procedures—are still experimental.
• Organ transplants extend survival but are constrained by donor supply, compatibility and lifelong immunosuppression, as researchers explore 3D‑printed, patient‑cell organs as a future alternative.