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Long-Term Use of Cardiovascular Drugs Linked to Lower Dementia Risk

Swedish study finds certain heart medications may reduce dementia risk by up to 25%, while others could increase it.

  • Researchers analyzed data from over 88,000 dementia patients and 880,000 controls in Sweden, focusing on individuals aged 70 and older.
  • Long-term use (five years or more) of antihypertensive drugs, cholesterol-lowering drugs, diuretics, and blood thinners was associated with a 4–25% reduced risk of dementia.
  • Combining multiple heart medications appeared to enhance their protective effects against dementia.
  • Antiplatelet drugs, often prescribed to prevent blood clots, were linked to an increased risk of dementia, potentially due to their association with microbleeds in the brain.
  • The study highlights the need for further research, including clinical trials, to understand the mechanisms behind these findings and explore preventive strategies for dementia.
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