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Long COVID Linked to Years-Long Work Disruption and Financial Toxicity

A JAMA Network Open analysis of over 3,600 INSPIRE participants highlights long COVID’s persistent economic toll three years post-infection

Overview

  • Individuals with long COVID faced more than threefold higher odds of moderate-to-high financial toxicity compared to those whose symptoms resolved and over fivefold higher odds compared to those never experiencing long COVID.
  • Nearly half of participants still reporting long COVID symptoms at three years had not returned to full-time work.
  • The analysis drew on self-reported data from more than 3,600 adults in the CDC-funded INSPIRE registry across eight U.S. academic medical centers.
  • Prior COVID-19 vaccination was associated with significantly lower rates of work impairment and financial distress among study participants.
  • Study authors attribute financial strain to medical expenses, job loss, reduced work hours and lower productivity and urge strengthened workplace and disability policies.