Overview

• Kick-off is 8pm BST at Anfield, with live coverage on ITV1 and Sky Sports and streams on ITVX and Sky Go.
• Slot has confirmed Mohamed Salah, Virgil van Dijk, Ibrahima Konate, Ryan Gravenberch and Dominik Szoboszlai will be rested.
• A heavily rotated XI is expected, with goalkeeper Giorgi Mamardashvili and defender Giovanni Leoni reported to be in contention for debuts.
• Liverpool enter the tie on a perfect league start with five wins, coming off a 3-2 victory over Atletico Madrid and a 2-1 derby win over Everton.
• Southampton are 19th in the Championship with one win from six after a 3-1 loss at Hull, and Will Still says he will use the match to give opportunities to fringe and youth players.