Overview

• Kick-off is 8pm BST at Anfield, with live coverage on ITV1/STV and Sky Sports plus streaming on ITVX and Sky Go.
• Arne Slot has ruled out Mohamed Salah, Virgil van Dijk, Ibrahima Konaté, Ryan Gravenberch and Dominik Szoboszlai for rest.
• Giorgi Mamardashvili and Giovanni Leoni are expected to feature, with competitive debuts widely tipped.
• Record signing Alexander Isak is likely to start as he builds fitness after recent substitute appearances.
• Liverpool enter on a six-game winning run and lead the Premier League by five points, while 19th-placed Southampton have one league win from six and are clear underdogs in betting markets.