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Liver Fat, Not Weight, Best Flags Metabolic Risk in Children With Obesity, Study Finds

Using MRI spectroscopy in 31 patients, Tel Aviv researchers tied higher hepatic fat to early metabolic abnormalities.

Overview

  • The cross-sectional analysis found average liver fat of about 14% in metabolically unhealthy participants versus about 6% in metabolically healthy peers.
  • Visceral fat and other measured factors did not differ significantly between groups, pointing to hepatic fat as the key discriminator.
  • Children already showing illness reported higher intake of sodium, processed foods, and saturated fats from red meat, and the authors pointed to a Mediterranean-style diet as a potential protective pattern.
  • Those in the unhealthy group were roughly three times more likely to have been born after high-risk pregnancies, indicating possible prenatal influences on later metabolic health.
  • The authors stress that the findings show correlation rather than causation and urge larger longitudinal studies, proposing noninvasive liver-focused screening and diet-based interventions; the study appears in Frontiers in Nutrition.