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Live Ocular Worm Removed by Vitrectomy in India

The patient underwent a novel surgical approach following eight months of eye inflammation leading to visual impairment.

Overview

  • A sluggish parasite was observed moving in the posterior segment of a 35-year-old man’s left eye after eight months of redness and blurred vision.
  • Pars plana vitrectomy suction was employed to extract the worm, which was removed tail-first while still alive.
  • Microscopic examination identified the nematode as a larval-stage Gnathostoma spinigerum based on its bulbous head, thick cuticle and developed intestine.
  • Postoperative treatment with oral and ocular glucocorticoids plus albendazole resolved inflammation, though an eight-week follow-up revealed a persistent cataract reducing vision to 20/40.
  • Gnathostoma spinigerum is endemic in India and typically cycles through carnivorous mammals and aquatic hosts, with human ocular infection remaining exceptionally rare.