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Rare Gnathostoma Worm Surgically Removed From Indian Man’s Eye

Researchers urge ophthalmologists in endemic regions to consider ocular gnathostomiasis when evaluating patients with unexplained ocular inflammation

Overview

  • A 35-year-old man from rural central India endured eight months of redness, blurred vision and panuveitis before funduscopy revealed a sluggish worm in his posterior segment.
  • Ophthalmologists performed a pars plana vitrectomy to suction out the live intraocular larva.
  • Microscopic analysis of the extracted specimen confirmed Gnathostoma spinigerum based on its cephalic bulb, thick cuticle and well-defined intestine.
  • Oral and ocular glucocorticoids plus albendazole resolved the infection, but at eight weeks a postoperative cataract limited vision in the affected eye to 20/40.
  • Researchers urge clinicians in endemic areas to consider ocular gnathostomiasis in patients with persistent uveitis and histories of undercooked freshwater fish or poultry consumption.