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Light-Based 3D Printing Breakthrough Paves Way for Advanced Regenerative Medicine

Terasaki Institute researchers develop customizable microgels guiding cellular organization and vascularization, with potential for minimally invasive tissue repair therapies.

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Overview

  • The Terasaki Institute has introduced a light-based 3D printing technique to fabricate microgels with precise architectures that guide cell growth and organization.
  • Published in the journal *Small*, the study demonstrates successful alignment of muscle cells into fibers and photoreceptor cells into retinal-like layers.
  • Incorporation of angiogenic peptides into the microgels promotes blood vessel growth both in vitro and in vivo, enhancing tissue viability.
  • The microgels retain their shape during injection, supporting applications in minimally invasive therapies such as muscle repair and retinal disease treatments.
  • Supported by funding from NIDDK and TIBI, the customizable platform is positioned for preclinical development in regenerative medicine.