Overview
- The round of 16 will be played from Saturday, November 22, through Wednesday, November 26, with eight single-elimination matches confirmed.
- Saturday opens with Vélez vs Argentinos in Liniers and Central Córdoba vs San Lorenzo in Santiago del Estero.
- Sunday features Rosario Central vs Estudiantes in Rosario and Boca vs Talleres at La Bombonera.
- Monday’s slate includes Deportivo Riestra vs Barracas Central, Racing vs River, and Unión vs Gimnasia in Santa Fe.
- Lanús hosts Tigre on Wednesday due to Lanús playing the Copa Sudamericana final on Saturday, and higher-seeded teams host through semifinals with the final at a neutral venue.