Overview
- Pumas UNAM host Querétaro at Estadio Olímpico Universitario, with kickoff listed at 13:00 in Colombia and Peru and a 12:00 start in Mexico on Canal de las Estrellas, TUDN and ViX Premium.
- Atlético de San Luis face Tigres at Estadio Alfonso Lastras Ramírez at 20:00 local time in Colombia and Peru in the final match of the opening round.
- Maximiliano Quintero Hernández is assigned to officiate Pumas vs. Querétaro, and Daniel Quintero Huitrón will referee San Luis vs. Tigres.
- The most recent meetings cited from Apertura 2025 saw Pumas defeat Querétaro 2–0 on July 25 and Tigres beat San Luis 3–1 on November 8.
- RPP lists the next several Clausura fixtures for all four clubs along with country-by-country kickoff times for regional audiences.