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Leipzig Metabolism Center Launches Personalized Chamber Study with DFG Backing

Researchers will measure oxygen uptake alongside carbon dioxide output across repeated 24-hour stays to reveal how diseased fat tissue fuels metabolic disorders

Overview

  • The study is now enrolling participants including children, athletes and individuals weighing up to 250 kilograms for multiple monitoring sessions
  • Each volunteer undergoes five separate 24-hour chamber stays paired with an 18-day diet tailored to assess energy balance rather than drive weight loss
  • Specialized metabolic chambers record oxygen consumption and carbon dioxide production to calculate precise individual energy expenditure
  • Led by HI-MAG director Matthias Blüher, the research seeks to clarify how pathological adipose tissue contributes to diabetes, heart disease, stroke, hypertension and certain cancers
  • Beginning in 2026, the Leipzig Center of Metabolism will receive a seven-year, multi-million-euro grant from the DFG Excellence Strategy to expand its clinical research infrastructure