Largest Study on Restless Leg Syndrome Reveals Over 140 Genetic Risk Factors

Cambridge-led research could transform diagnosis and treatment, potentially improving millions of lives.

Researchers identified 164 genetic loci linked to restless leg syndrome, significantly expanding previous knowledge.
The study involved data from over 100,000 patients and 1.5 million controls.
Findings suggest no strong genetic differences between men and women, despite higher prevalence in women.
The condition, affecting up to 10% of older adults, can cause severe sleep disruption and other health issues.
Potential treatments may target newly identified genetic markers related to nerve and brain function.