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Largest Post-COVID Smell Study Finds Lasting Loss, Often Without Symptoms

Objective testing of 3,535 adults about two years after infection detected widespread hyposmia, prompting calls for routine screening.

Overview

  • The RECOVER cohort reported that 80% of people who noticed smell changes after COVID-19 still scored low on testing, with 23% severely impaired or anosmic.
  • Two-thirds of infected participants who perceived no smell problem nonetheless had abnormal results on the 40-odor University of Pennsylvania Smell Identification Test.
  • The multicenter study is the largest objective assessment of post-COVID olfaction to date and was published Sept. 25 in JAMA Network Open.
  • Investigators recommend adding smell checks to post-COVID care, citing safety and quality-of-life risks from undetected hyposmia, including difficulty detecting spoiled food, gas leaks, and smoke.
  • Authors note limits such as no direct taste assessment and possible misclassification of uninfected participants, which could inflate impairment rates in comparison groups.