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Large UK Study Links Severe Vitamin D Deficiency to Higher Respiratory Infection Hospitalizations

Researchers say the findings support winter supplementation guidance.

Overview

  • An analysis of 36,258 UK Biobank participants found that people with vitamin D levels below 15 nmol/L had a 33% higher rate of hospital admission for respiratory tract infections than those at or above 75 nmol/L.
  • Each 10 nmol/L increase in circulating vitamin D was associated with an approximate 4% reduction in hospitalizations for infections such as bronchitis and pneumonia.
  • The University of Surrey led the observational study with collaborators at Oxford and Reading, and the results were published in The American Journal of Clinical Nutrition.
  • The authors point to older adults and ethnic minority communities as priority groups for raising vitamin D levels through supplements or fortified foods.
  • Researchers emphasize that the findings show association rather than causation and call for interventional studies, while NHS advice continues to recommend a daily supplement during autumn and winter.